Molecular recognition in a lattice model: an enumeration study.

نویسندگان

  • Thorsten Bogner
  • Andreas Degenhard
  • Friederike Schmid
چکیده

We investigate the mechanisms underlying selective molecular recognition of single heteropolymers at chemically structured planar surfaces. To this end, we study systems with two-letter (HP) lattice heteropolymers by exact enumeration techniques. Selectivity for a particular surface is defined by an adsorption energy criterion. We analyze the distributions of selective sequences and the role of mutations. A particularly important factor for molecular recognition is the small-scale structure on the polymers.

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عنوان ژورنال:
  • Physical review letters

دوره 93 26 Pt 1  شماره 

صفحات  -

تاریخ انتشار 2004